Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50034933
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070352(1-benzyl-5-(3,4-dichlorophenyl)-5-{3-[1-methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070358(8-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piper...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070356(5-[3-(4-Acetyl-4-phenyl-piperidin-1-yl)-propyl]-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070353(1-(1-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-pi...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070354(8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070355(3-(3,4-dichlorophenyl)-3-{3-[1-methylsulfonylspiro...)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070360(3-(3,4-dichlorophenyl)-3-[3-spiro[2,3-dihydro-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 204nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070359(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 348nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Sharp Laboratory

Curated by ChEMBL
LigandPNGBDBM50070351(1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperid...)copy SMILEScopy InChI
Affinity DataIC50: 389nMAssay Description:Compound was evaluated for affinity towards human Neurokinin NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3N16PubMed