Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50035964
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006981(CHEMBL19841 | [1-Methyl-2-(3-trifluoromethyl-pheny...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006982(CHEMBL281619 | [2-(3-Bromo-phenyl)-1-methyl-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006974(CHEMBL53253 | [1-Methyl-2-(4-propyl-phenyl)-ethyl]...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006972((1-Methyl-2-naphthalen-2-yl-ethyl)-(3-phenyl-propy...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006968((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocycl...)copy SMILEScopy InChI
Affinity DataKi:  7.90nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)copy SMILEScopy InChI
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006973(CHEMBL298758 | [2-(3,4-Dichloro-phenyl)-1-methyl-e...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006971((1-Methyl-2-naphthalen-1-yl-ethyl)-(3-phenyl-propy...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006980((3-Phenyl-propyl)-(1,2,3,4-tetrahydro-naphthalen-2...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041279(((R)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50041261(((S)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006977(CHEMBL55317 | Indan-2-yl-(3-phenyl-propyl)-amine)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50006979((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocycl...)copy SMILEScopy InChI
Affinity DataKi:  83nMAssay Description:Inhibition of [3H]DTG binding to Sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7J9ZPubMed