Compile Data Set for Download or QSAR
Found 20 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50039245
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322794(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322784(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322793(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322790(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322787(6-(4-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM25458((1S,2R,5S,10R,11S,15S)-2,15-dimethyl-14-(pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322792(3-fluoro-4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322786(4'-(2-methyl-1-(pyridin-4-yl)prop-1-enyl)biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322789(4'-(pyridin-4-ylmethyl)biphenyl-3-ol | 4-[(3'-Hydr...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322791(3-Fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol | CH...)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322795(4'-(1-(pyridin-4-yl)propyl)biphenyl-3-ol | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322783(4'-(pyridin-4-ylmethyl)biphenyl-3-amine | CHEMBL11...)copy SMILEScopy InChI
Affinity DataIC50: 226nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322785(4'-(Pyridin-4-ylmethyl)biphenyl-3,4-diamine | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 337nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322797(3-fluoro-4'-(1-(pyridin-4-yl)propyl)biphenyl-4-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 343nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322799(CHEMBL1173727 | tert-butyl 4'-(2-methyl-1-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 493nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322796(4'-(2-methyl-1-(pyridin-4-yl)propyl)biphenyl-3-ol ...)copy SMILEScopy InChI
Affinity DataIC50: 783nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322800(CHEMBL1173795 | tert-butyl 3-fluoro-4'-(2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 852nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322798(CHEMBL1173726 | tert-butyl 4'-(2-methyl-1-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50322801(CHEMBL1173796 | tert-butyl 4'-(2-methyl-1-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli coexpressing NADPH-P450 reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37X9KPubMed