Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50040568
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396180(CHEMBL2171897)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396181(CHEMBL2172017)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396183(CHEMBL2172015)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM20273((2S)-2-[(2S)-2-[(4-cyanophenyl)formamido]-3-[4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50382459(CHEMBL2023986 | US10196373, Compound 27NH)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396179(CHEMBL2172013)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396178(CHEMBL2172014)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50382461(CHEMBL2023987 | US10196373, Compound 27KG)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM20282(4-{[4-(hexylcarbamoyl)-2-(naphthalen-1-yl)-1,3-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM20283(2-hydroxy-4-(2-{[(4-methylbenzene)sulfonyl]oxy}ace...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396182(CHEMBL2172016)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8FKKPubMed