Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50045863
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086681(CHEMBL3426309)copy SMILES
Affinity DataKi:  0.0900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086604(CHEMBL3426308)copy SMILES
Affinity DataKi:  0.200nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086605(CHEMBL3426307)copy SMILES
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086659(CHEMBL3426303)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086671(CHEMBL3426305)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086659(CHEMBL3426303)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086671(CHEMBL3426305)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086676(CHEMBL3426304)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086680(CHEMBL3426306)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086669(CHEMBL3426301)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086669(CHEMBL3426301)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086667(CHEMBL3426302)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086667(CHEMBL3426302)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022933(CHEMBL3298288)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022930(CHEMBL3298374)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022931(CHEMBL3298369)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022931(CHEMBL3298369)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086605(CHEMBL3426307)copy SMILES
Affinity DataKi: >400nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed