Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50047984
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199870(CHEMBL3904593)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199858(CHEMBL3956814)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199871(CHEMBL3920126)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199869(CHEMBL3929254)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199868(CHEMBL3906283)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed