Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 5757
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93118(PTP1B Inhibitor, 19)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nM IC50: 6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93109(PTP1B Inhibitor, 5)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nM IC50: 7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93111(PTP1B Inhibitor, 7)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nM IC50: 8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93113(PTP1B Inhibitor, 11)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nM IC50: 6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93112(PTP1B Inhibitor, 10)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nM IC50: 6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487364(CHEMBL2259741)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487368(CHEMBL2259740)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93110(PTP1B Inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  5.60E+4nM IC50: 9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93116(PTP1B Inhibitor, 14)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nM IC50: 8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487366(CHEMBL2259730)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93117(PTP1B Inhibitor, 15)copy SMILEScopy InChI
Affinity DataKi:  1.35E+5nM IC50: 1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487365(CHEMBL2259731)copy SMILEScopy InChI
Affinity DataKi:  1.35E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93115(PTP1B Inhibitor, 13)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nM IC50: 2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487367(CHEMBL2259743)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93114(PTP1B Inhibitor, 12)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nM IC50: 4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487369(CHEMBL2259742)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487364(CHEMBL2259741)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487368(CHEMBL2259740)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50182135(3-(4-methoxybenzofuran-5-yl)-5-phenyl-4,5-dihydroi...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50182133(3-(4-methoxybenzofuran-5-yl)-5-(4-methoxyphenyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487366(CHEMBL2259730)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487365(CHEMBL2259731)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487367(CHEMBL2259743)copy SMILEScopy InChI
Affinity DataIC50: 2.75E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487369(CHEMBL2259742)copy SMILEScopy InChI
Affinity DataIC50: 4.85E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG