Found 3 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 952 TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
AbbVie S.á.r.l.; Galapagos NV
US Patent
AbbVie S.á.r.l.; Galapagos NV
US Patent
Affinity DataIC50: 102nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
AbbVie S.á.r.l.; Galapagos NV
US Patent
AbbVie S.á.r.l.; Galapagos NV
US Patent
Affinity DataIC50: 417nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
AbbVie S.á.r.l.; Galapagos NV
US Patent
AbbVie S.á.r.l.; Galapagos NV
US Patent
Affinity DataIC50: 496nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
