TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.398nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.631nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Heptares Therapeutics Ltd.
Curated by ChEMBL
Heptares Therapeutics Ltd.
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
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