Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for assayid = 17 entry = 50005549
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038169((3R,4R)-3-Amino-1-hydroxy-4-methyl-pyrrolidin-2-on...)copy SMILEScopy InChI
Affinity DataKi:  650nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28PTPubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038175((3R,4R)-3-Amino-1,4-dihydroxy-pyrrolidin-2-one | C...)copy SMILEScopy InChI
Affinity DataKi:  750nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28PTPubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038159((R)-3-Amino-1-hydroxy-pyrrolidin-2-one | CHEMBL335...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28PTPubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50038157(6-Hydroxy-2,6-diaza-bicyclo[3.2.1]octan-7-one | CH...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cortical neuron at NMDA receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM28PTPubMed