Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for assayid = 17 entry = 50033562
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B858GZPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50347388(CHEMBL1234833)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B858GZPubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B858GZPubMed