Compile Data Set for Download or QSAR
Found 33 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50001996
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451743(CHEMBL4205065)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220218(US9290476, 61)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451754(CHEMBL4217859)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451750(CHEMBL4204175)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451750(CHEMBL4204175)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451742(CHEMBL4209998)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220238(US9290476, 83A | US9290476, 83B | US9290476, 83C)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220238(US9290476, 83A | US9290476, 83B | US9290476, 83C)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220217(US9290476, 60A | US9290476, 60B | US9290476, 60C)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50239063(CHEMBL4094197)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220190(US9290476, 33A | US9290476, 33B | US9290476, 33C)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220190(US9290476, 33A | US9290476, 33B | US9290476, 33C)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451748(CHEMBL4218386)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220192(US9290476, 35A | US9290476, 35B | US9290476, 35C)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM220192(US9290476, 35A | US9290476, 35B | US9290476, 35C)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451806(CHEMBL4209944)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451747(CHEMBL4205629)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451745(CHEMBL4214388)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451755(CHEMBL4213458)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451751(CHEMBL4216372)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451807(CHEMBL4218239)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50239053(CHEMBL4071285)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50239053(CHEMBL4071285)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50239053(CHEMBL4071285)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451752(CHEMBL4209983)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451752(CHEMBL4209983)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451744(CHEMBL4207122)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451749(CHEMBL4206508)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451741(CHEMBL4211999)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451808(CHEMBL4211066)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451753(CHEMBL4208253)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC

Curated by ChEMBL
LigandPNGBDBM50451746(CHEMBL4210499)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BN5PubMed