TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 820nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Research and Development, LLC
Curated by ChEMBL
Janssen Research and Development, LLC
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inverse agonist activity at GAL4 DBD-fused wild type human RORgammat LBD (850 to 1635 residues) expressed in HEK293T cells assessed as inhibition of ...More data for this Ligand-Target Pair