Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50013983
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136662((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136661((R)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136644((S)-2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136648((S)-2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136667(2-Amino-1-[(S)-5-chloro-2-(5-propyl-1H-imidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136654((S)-2-Amino-3-methyl-1-[(S)-2-(5-propyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121285((S)-2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136663(2-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136636(2-Amino-1-[(S)-5-fluoro-2-(5-propyl-1H-imidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136660(2-Amino-1-[(S)-5-methoxy-2-(5-propyl-1H-imidazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136652(2-Amino-1-[(S)-2-(5-ethyl-1H-imidazol-2-yl)-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136658(CHEMBL138313 | [(S)-2-(5-Propyl-1H-imidazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136647((S)-2-Amino-3-phenyl-1-[(S)-2-(5-propyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136657((2-Nitro-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136653((3-Nitro-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136649((3-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136643((S)-2-[(S)-2-(5-Ethyl-1H-imidazol-2-yl)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136642((S)-2-Methylamino-1-[(S)-2-(5-propyl-1H-imidazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136640((2-Amino-phenyl)-[(S)-2-(5-propyl-1H-imidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136669((1H-Imidazol-4-yl)-[(S)-2-(5-propyl-1H-imidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50136639(3-Amino-1-[(S)-2-(5-propyl-1H-imidazol-2-yl)-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289159PPubMed