Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50014839
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091817(4-Methyl-6-propyl-pyridin-2-ylamine | 4-Methyl-6-p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148168((E)-8-Propyl-3,4,5,6,7,8-hexahydro-azocin-2-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50124535(1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091805(2-amino-4,6-dimethylpyridine | 4,6-Dimethyl-pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148169((4-Chloro-phenyl)-[4-(4-methoxy-pyridin-2-ylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148167(4-(4-(4-methoxypyridin-2-ylamino)piperidine-1-carb...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148164(4-(4-Methoxy-pyridin-2-ylamino)-piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091800(2-amino-4-methylpyridine | 4-METHYLPYRIDIN-2-AMINE...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148162(4-(4-Methyl-pyridin-2-ylamino)-piperidine-1-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148163(CHEMBL112747 | [4-(4-Methoxy-pyridin-2-ylamino)-pi...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148170(4-Methoxy-pyridin-2-ylamine | CHEMBL113793)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50091813(4-Ethyl-pyridin-2-ylamine | 4-ethylpyridin-2-amine...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148166(4-(4-Ethoxy-pyridin-2-ylamino)-piperidine-1-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148171(4-(Pyridin-2-ylamino)-piperidine-1-carboxylic acid...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
AstraZeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148165((4,6-Dimethyl-pyridin-2-yl)-methyl-amine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+4nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M656DPubMed