Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50015338
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585613(CHEMBL5088349)copy SMILES
Affinity DataIC50: 460nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520645(CHEMBL2347859 | US11279719, Example C-5)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50585614(CHEMBL5082193)copy SMILES
Affinity DataIC50: 730nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520637(CHEMBL4577077 | US11279719, Example I-37)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))TBA
LigandPNGBDBM50520639(CHEMBL4465832 | US11279719, Example I-6)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human FPPS expressed in Escherichia coli BL21 (DE3) preincubated for 10 mins in presence compound relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7F00PubMed