Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50015848
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161617(8-Methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]a...)copy SMILEScopy InChI
Affinity DataEC50:  940nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161622(8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]aze...)copy SMILEScopy InChI
Affinity DataEC50:  510nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161625(1-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine | C...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161632(7-Bromo-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]az...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161633((1R,S)-8-chloro-7-fluoro-2,3,4,5-tetrahydro-1-meth...)copy SMILEScopy InChI
Affinity DataEC50:  72nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161637((R)-8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-...)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161626(8-Bromo-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]aze...)copy SMILEScopy InChI
Affinity DataEC50:  63nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161641((1R,S)-7,8-dichloro-2,3,4,5-tetrahydro-1-methyl-1H...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161642((1R,S)-7-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161627((1R,S)-8-fluoro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161619(7-Methoxy-1-methyl-8-trifluoromethyl-2,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataEC50:  42nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161638((1R,S)-8-chloro-7-methoxy-2,3,4,5-tetrahydro-1-met...)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161646((1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-ben...)copy SMILEScopy InChI
Affinity DataEC50:  190nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161645(7-Chloro-2,3,4,5-tetrahydro-1H-benzo[d]azepine | C...)copy SMILEScopy InChI
Affinity DataEC50:  90nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161628((1R,S)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...)copy SMILEScopy InChI
Affinity DataEC50:  260nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161624((S)-8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-...)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161647((1S)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-ben...)copy SMILEScopy InChI
Affinity DataEC50:  265nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161618(7-Benzyloxy-8-bromo-1-methyl-2,3,4,5-tetrahydro-1H...)copy SMILEScopy InChI
Affinity DataEC50:  22nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161631((1R,S)-9-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161634((1R)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161648((1R,S)-6,8-dichloro-2,3,4,5-tetrahydro-1-methyl-1H...)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161636((1S)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H-3...)copy SMILEScopy InChI
Affinity DataEC50:  135nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161644(7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]a...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161639((1R,S)-8-chloro-9-fluoro-2,3,4,5-tetrahydro-1-meth...)copy SMILEScopy InChI
Affinity DataEC50:  840nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161623(8-Bromo-1-ethyl-7-methoxy-2,3,4,5-tetrahydro-1H-be...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161635(8-Bromo-7-ethoxy-1-methyl-2,3,4,5-tetrahydro-1H-be...)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161620(8-Bromo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-b...)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161629((1R,S)-8,9-dichloro-2,3,4,5-tetrahydro-1-methyl-1H...)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161643(8-Iodo-7-methoxy-1-methyl-2,3,4,5-tetrahydro-1H-be...)copy SMILEScopy InChI
Affinity DataEC50:  61nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161649((1R,S)-8-trifluoromethyl-2,3,4,5-tetrahydro-1-meth...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161630(8-Bromo-7-isopropoxy-1-methyl-2,3,4,5-tetrahydro-1...)copy SMILEScopy InChI
Affinity DataEC50:  97nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50161621((1R,S)-6-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-b...)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK-293 cells was determined by measuring [3H]-phosphoinositol releas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6Q0GPubMed