Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50028967
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from marmoset gutMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280418(2-[4-(1-Methyl-1H-imidazol-2-ylsulfanyl)-butylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280422(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280420(1-[6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-hexyl...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280421(2-[5-(1H-Imidazol-2-ylsulfanyl)-pentylsulfanyl]-4,...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280416(2-[3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-propylsul...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280417(1-[3-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-propy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280419(2-[3-(1-Methyl-1H-imidazole-2-sulfonyl)-propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G