Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50032741
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333983(4-(8-chloronaphthalen-2-yl)-3-(2-(tetrahydro-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334001(3-(2-(cyclohexylamino)pyridin-4-yl)-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334000(3-(2-(cyclohexylamino)pyridin-4-yl)-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333997(CHEMBL1644646 | methyl 4-(4-(naphthalen-2-yl)-5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334008(3-(2-(cyclohexylamino)pyridin-4-yl)-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333980(3-(2-(cyclohexylamino)pyridin-4-yl)-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333987(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333989(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333982(4-(naphthalen-2-yl)-3-(2-(pyridin-2-ylamino)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334007(4-(naphthalen-2-yl)-1-(pyridin-2-ylmethyl)-3-(2-(t...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333998(4-(8-fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334003(4-(naphthalen-2-yl)-3-(2-(phenylamino)pyridin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333992(3-(2-(cyclobutylamino)pyridin-4-yl)-4-(naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333990(4-(6-fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333994(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333996(4-(naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334004(4-(8-aminonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333981(4-(naphthalen-2-yl)-1-(pyridin-2-yl)-3-(2-(tetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333984(CHEMBL1644630 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333985(3-(2-(cyclopentylamino)pyridin-4-yl)-4-(naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333986(3-(2-(cyclopropylamino)pyridin-4-yl)-4-(naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333988(4-(naphthalen-2-yl)-1-(piperidin-4-yl)-3-(2-(tetra...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333991(4-(naphthalen-2-yl)-3-(2-(thiazol-2-ylamino)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333993(4-(naphthalen-2-yl)-3-(2-(pyridin-3-ylamino)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333995(1-(1-ethylpiperidin-4-yl)-4-(naphthalen-2-yl)-3-(2...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50333999(CHEMBL1644629 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334002(4-(6-bromonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334005(CHEMBL1644631 | N-(4-(4-(naphthalen-2-yl)-5-oxo-4,...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334006(4-(6-aminonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334010((S)-4-(naphthalen-2-yl)-3-(2-(1-phenylethylamino)p...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334009(4-(naphthalen-2-yl)-3-(pyridin-4-yl)-1H-1,2,4-tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1R0TPubMed