Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50033107
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)copy SMILEScopy InChI
Affinity DataKi:  71.9nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339680(CHEMBL1688930 | S-(2-Methyl-1,1-diphenylbutyl)-L-c...)copy SMILEScopy InChI
Affinity DataKi:  76.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339673(CHEMBL1688927 | S-(1,1-Diphenyl[4-(butyl)phenyl]me...)copy SMILEScopy InChI
Affinity DataKi:  84.2nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50198302((S)-2-amino-3-(tritylthio)propanoic acid | CHEMBL3...)copy SMILEScopy InChI
Affinity DataKi:  98.6nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM23802(2-[(triphenylmethyl)sulfanyl]ethan-1-amine | Triph...)copy SMILEScopy InChI
Affinity DataKi:  156nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM23777((2R)-2-amino-3-[(2-methyl-1,1-diphenylpropyl)sulfa...)copy SMILEScopy InChI
Affinity DataKi:  175nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339681(CHEMBL1688931 | S-(2-Ethyl-1,1-diphenylbutyl)-L-cy...)copy SMILEScopy InChI
Affinity DataKi:  302nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339672(CHEMBL1688926 | S-(1,1-Diphenyl[4-(tert-butyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  429nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339671(CHEMBL1688925 | S-(1,1-Diphenyl[4-biphenyl]methyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.35E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339679(4-((2-amino-2-carboxyethylthio)diphenylmethyl)benz...)copy SMILEScopy InChI
Affinity DataKi:  2.54E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339670(CHEMBL1688924 | S-(1,1-Diphenyl[4-(cyclohexyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  3.26E+3nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50339682((R)-2-amino-3-(diphenyl(thiophen-2-yl)methylthio)p...)copy SMILEScopy InChI
Affinity DataKi:  5.83E+4nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154HC9PubMed