Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50033894
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353440(CHEMBL1829864 | US10196373, Compound 45F)copy SMILEScopy InChI
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353442(CHEMBL1829871 | US10196373, Compound 45E)copy SMILEScopy InChI
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353439(CHEMBL1829872 | US10196373, Compound 45G)copy SMILEScopy InChI
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353441(CHEMBL1829786)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353445(CHEMBL1829862 | US10196373, Compound 45B)copy SMILEScopy InChI
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353433(CHEMBL1829868 | US10196373, Compound 45N)copy SMILEScopy InChI
Affinity DataIC50: 6.22E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353444(CHEMBL1829870 | US10196373, Compound 45C)copy SMILEScopy InChI
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353435(CHEMBL1829874 | US10196373, Compound 45K)copy SMILEScopy InChI
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353447(CHEMBL1829875 | US10196373, Compound 45M)copy SMILEScopy InChI
Affinity DataIC50: 6.74E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353443(CHEMBL1829863 | US10196373, Compound 45D)copy SMILEScopy InChI
Affinity DataIC50: 7.92E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353436(CHEMBL1829866 | US10196373, Compound 45J)copy SMILEScopy InChI
Affinity DataIC50: 9.03E+4nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353446(CHEMBL1829869 | US10196373, Compound 45A)copy SMILEScopy InChI
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353437(CHEMBL1829873 | US10196373, Compound 45I)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353434(CHEMBL1829867 | US10196373, Compound 45L)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50353438(CHEMBL1829865 | US10196373, Compound 45H)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of STAT3 in mouse NIH3T3/vSrc nuclear extract assessed as disruption of the Stat3-DNA complex pre-incubated for 30 mins by EMSA analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966R9PubMed