Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50034473
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50363052(CHEMBL1946956)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50363017(CHEMBL1945812)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50343350(4,4,4-trifluoro-1-(4-(3-(thiophen-2-yl)-1,2,4-oxad...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9CJWPubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50343351(4,4,4-Trifluoro-1-[(R)-3-(3-thiophen-2-yl-1,2,4-ox...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9CJWPubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50363015(CHEMBL1945701)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis)
Universit£ Lille Nord de France

Curated by ChEMBL
LigandPNGBDBM50363018(CHEMBL1945813)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of EthR binding to ethA promoter in 106-bp biotinylated DNA preincubated for 5 mins measured for 3 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair