Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50035837
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50014156(4-(2-Methoxy-phenyl)-2-(5-methyl-1H-imidazol-4-ylm...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995S5PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50014164(8-[2-(5-Methyl-1H-imidazol-4-ylmethyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995S5PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50014154(2-(5-Methyl-1H-imidazol-4-ylmethyl)-4-phenyl-thiaz...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995S5PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50014159(4-(2-Fluoro-phenyl)-2-(5-methyl-1H-imidazol-4-ylme...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995S5PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM50013043(3-[2-(5-Methyl-1H-imidazol-4-ylmethyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995S5PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Pfizer central Research

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair