Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50040625
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397228(CHEMBL2172775)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397227(CHEMBL2172776)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397226(CHEMBL2172777)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397225(CHEMBL2172778)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397229(CHEMBL2172774)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397224(CHEMBL2172779)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397234(CHEMBL2172767)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397233(CHEMBL2172768)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397231(CHEMBL2172771)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397235(CHEMBL2172791)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397232(CHEMBL2172770)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397230(CHEMBL2172772)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397237(CHEMBL2172788)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397236(CHEMBL2172790)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397238(CHEMBL2172786)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Eberhard Karls University

Curated by ChEMBL
LigandPNGBDBM50397239(CHEMBL2172780)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as inhibition of PGE2 formation from PGH2 after 15 mins by RP-HPLC a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z74FDPubMed