Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50044720
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027472(CHEMBL2297684)copy SMILEScopy InChI
Affinity DataEC50:  2.50E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  1.16E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027483(CHEMBL3335590 | US11866416, Compound 9b)copy SMILEScopy InChI
Affinity DataEC50:  6.10E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027484(CHEMBL3335591 | US11866416, Compound 21b)copy SMILEScopy InChI
Affinity DataEC50:  3.80E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027474(CHEMBL3335592)copy SMILEScopy InChI
Affinity DataEC50:  3.30E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027485(CHEMBL3335593)copy SMILEScopy InChI
Affinity DataEC50:  8.90E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50042993((2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl...)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027486(CHEMBL3335594)copy SMILEScopy InChI
Affinity DataEC50:  6.70E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027487(CHEMBL3335595)copy SMILEScopy InChI
Affinity DataEC50:  5.40E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027488(CHEMBL3335596)copy SMILEScopy InChI
Affinity DataEC50:  1.07E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027489(CHEMBL3335597)copy SMILEScopy InChI
Affinity DataEC50:  7.30E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027490(CHEMBL3335598)copy SMILEScopy InChI
Affinity DataEC50:  1.72E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027491(CHEMBL3335599)copy SMILEScopy InChI
Affinity DataEC50:  3.90E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027492(CHEMBL3335600)copy SMILEScopy InChI
Affinity DataEC50:  2.60E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027493(CHEMBL3335601)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50374402(CHEMBL257591 | PNU-120596)copy SMILEScopy InChI
Affinity DataEC50:  3.80E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50374403(CHEMBL412119)copy SMILEScopy InChI
Affinity DataEC50:  5.50E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50250187(4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027475((E)-1-(2,4-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027481((E)-1-(2,5-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Instituto de Qu£mica M£dica (IQM-CSIC)

Curated by ChEMBL
LigandPNGBDBM50027482(CHEMBL1256531 | US11866416, Compound SN-II-32)copy SMILEScopy InChI
Affinity DataEC50:  3.45E+4nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN977TPubMed