Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50049201
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236287(CHEMBL4071967)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236321(CHEMBL4097389)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236319(CHEMBL4101407)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236323(CHEMBL4070144)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236290(CHEMBL4083419)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236320(CHEMBL4091106)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Affinity towards human M1 receptor expressed in CHO cells using [3H]QNB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236285(CHEMBL4098009)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236282(CHEMBL4104895)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236289(CHEMBL4082453)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236322(CHEMBL4080662)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236291(CHEMBL4060570)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236286(CHEMBL4079985)copy SMILEScopy InChI
Affinity DataIC50: 3.59E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236283(CHEMBL4074887)copy SMILEScopy InChI
Affinity DataIC50: 4.33E+4nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236288(CHEMBL4098945)copy SMILEScopy InChI
Affinity DataIC50: 4.45E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM29143(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)copy SMILEScopy InChI
Affinity DataIC50: 4.64E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed
TargetThioredoxin reductase 1, cytoplasmic(Rattus norvegicus)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50236284(CHEMBL4069255)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of recombinant rat liver thioredoxin reductase after 30 mins by DTNB reduction assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2K2VPubMed