Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 7592
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM50323697((3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL...)copy SMILEScopy InChI
Affinity DataEC50:  13nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205418(US9243020, (3aR,5R,6S,7R,7aR)-2-(ethylamino)-5-(hy...)copy SMILEScopy InChI
Affinity DataEC50:  10nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205420(US9243020, 2 | US9815861, Example 2)copy SMILEScopy InChI
Affinity DataEC50:  365nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205425(US9243020, 20 | US9815861, Example 20)copy SMILEScopy InChI
Affinity DataEC50:  6nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205422(US9243020, 9 | US9815861, Example 9)copy SMILEScopy InChI
Affinity DataEC50:  307nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)copy SMILEScopy InChI
Affinity DataEC50:  34nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205424(US9243020, 19 | US9815861, Example 19)copy SMILEScopy InChI
Affinity DataEC50:  53nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Alectos Therapeutics Inc.; Merck Sharp & Dohme Corp.

US Patent
LigandPNGBDBM205421(US9243020, 4 | US9815861, Example 4)copy SMILEScopy InChI
Affinity DataEC50:  358nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MD4US Patent