Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50000599
TargetKappa-type opioid receptor(Homo sapiens (Human))
Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Curated by ChEMBL
LigandPNGBDBM50254704(CHEMBL4073100)copy SMILEScopy InChI
Affinity DataEC50:  4.13E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25TPPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)copy SMILEScopy InChI
Affinity DataEC50:  8.99E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25TPPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Curated by ChEMBL
LigandPNGBDBM50003755((2R)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(p...)copy SMILEScopy InChI
Affinity DataEC50:  57nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25TPPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Curated by ChEMBL
LigandPNGBDBM214799(1xx)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25TPPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Curated by ChEMBL
LigandPNGBDBM50254705(CHEMBL4068633)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as beta-arrestin2 recruitment by enzyme fragment complementation meth...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N25TPPubMed