Compile Data Set for Download or QSAR
Found 22 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50001625
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288437(CHEMBL4165758)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:GRAC: human PDE2A selective inhibitorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288438(CHEMBL4173676)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288512(CHEMBL4163122)copy SMILEScopy InChI
Affinity DataIC50: 347nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288515(CHEMBL4165506)copy SMILEScopy InChI
Affinity DataIC50: 357nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288378(CHEMBL4162065)copy SMILEScopy InChI
Affinity DataIC50: 363nMAssay Description:GRAC: human PDE2A selective inhibitorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288440(CHEMBL4174879)copy SMILEScopy InChI
Affinity DataIC50: 376nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288374(CHEMBL4169982)copy SMILEScopy InChI
Affinity DataIC50: 417nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288439(CHEMBL4163817)copy SMILEScopy InChI
Affinity DataIC50: 722nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288376(CHEMBL4177188)copy SMILEScopy InChI
Affinity DataIC50: 817nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288511(CHEMBL4171692)copy SMILEScopy InChI
Affinity DataIC50: 929nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288372(CHEMBL4173429)copy SMILEScopy InChI
Affinity DataIC50: 951nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288442(CHEMBL4173835)copy SMILEScopy InChI
Affinity DataIC50: 996nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288441(CHEMBL4166565)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288443(CHEMBL4166989)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288513(CHEMBL4162314)copy SMILEScopy InChI
Affinity DataIC50: 6.41E+3nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288514(CHEMBL4170235)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288379(CHEMBL4175654)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288377(CHEMBL4165365)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288373(CHEMBL4175808)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288436(CHEMBL4169221)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288510(CHEMBL4168613)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50288375(CHEMBL4159048)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells using 5FAM-GEEPLYWSFPAKKK-NH2 as substrate after 10 mins by cal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3PP4PubMed