Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50027115
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMedDrugBank
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263659(CHEMBL476131 | N-[2-(3-(3-hydroxymethylphenyl)-7-m...)copy SMILEScopy InChI
Affinity DataEC50:  0.760nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263602(CHEMBL453138 | N-[2-(3-phenyl-7-methoxynaphth-1-yl...)copy SMILEScopy InChI
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50035179(Agomelatine | CHEMBL10878 | N-[2-(7-Methoxy-naphth...)copy SMILEScopy InChI
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMedDrugBank
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263713(CHEMBL491604 | N-[2-(3-(3-Formylphenyl)-7-methoxyn...)copy SMILEScopy InChI
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263600(CHEMBL478217 | N-[2-(3-(3-Dimethylaminophenyl)-7-m...)copy SMILEScopy InChI
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263662(CHEMBL476341 | N-[2-(3-(3-Hydroxymethylphenyl)-7-m...)copy SMILEScopy InChI
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263716(CHEMBL490595 | N-[2-(3-(3-Bromomethylphenyl)-7-met...)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263758(CHEMBL490188 | N-[2-(3-(3-Aminophenyl)-7-methoxyna...)copy SMILEScopy InChI
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263551(CHEMBL477835 | N-[2-(3-(3-Methylaminophenyl)-7-met...)copy SMILEScopy InChI
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University of Lille 2

Curated by ChEMBL
LigandPNGBDBM50263661(CHEMBL518113 | N-[2-(3-(3-Hydroxymethylphenyl)-7-m...)copy SMILEScopy InChI
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B314NPubMed