Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50032438
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329205(5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329203(5-(4-chlorophenyl)-N-((2-(2,2,2-trifluoroethoxy)py...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329206(5-(4-chlorophenyl)-N-((2-ethoxypyridin-3-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329217(CHEMBL1271106 | N-(2-Methylbenzyl)-6-(4-trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329209(5-(4-chlorophenyl)-N-(2-(piperidin-1-yl)benzyl)nic...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329210(CHEMBL1269883 | N-(2-chlorobenzyl)-5-(4-chlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329212(CHEMBL1271417 | N-benzyl-5-(4-chlorophenyl)nicotin...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329213(5-(4-chlorophenyl)-N-(3,5-dimethylphenyl)nicotinam...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329202(5-(4-cyanophenyl)-N-(3,5-dimethylphenyl)nicotinami...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329215(CHEMBL1271206 | N-(3,5-dimethylphenyl)-5-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329204(5-(4-chlorophenyl)-N-((2-morpholinopyridin-3-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212239(5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329208(5-(4-chlorophenyl)-N-(2-morpholinobenzyl)nicotinam...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329223(CHEMBL1270797 | N-(3,5-dimethylphenyl)-5-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329214(CHEMBL1271415 | N-(3,5-dimethylphenyl)-5-(4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329219(CHEMBL1270999 | N-(3,5-dimethylphenyl)-2-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329216(CHEMBL1271205 | N-(3,5-dimethylphenyl)-6-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329218(CHEMBL1271105 | N-(3,5-dimethylphenyl)-5-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329207(5-(4-chlorophenyl)-N-((2-chloropyridin-3-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329220(CHEMBL1270998 | N-(3,5-dimethylphenyl)-3-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329222(CHEMBL1270898 | N-(3,5-dimethylphenyl)-2-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50329221(CHEMBL1270899 | N-(3,5-dimethylphenyl)-2-(4-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76CS6PubMed