Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50042642
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)copy SMILEScopy InChI
Affinity DataEC50:  2.33E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50085042(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)copy SMILEScopy InChI
Affinity DataEC50:  3.35E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC62JKPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM28701(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)copy SMILEScopy InChI
Affinity DataEC50:  4.66E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50299413((3',5'-dimethoxy-7-hydroxyisoflavone) | CHEMBL5750...)copy SMILEScopy InChI
Affinity DataEC50:  2.46E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC62JKPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50299415(4'-fluoro-7-hydroxyisoflavone | CHEMBL583378)copy SMILEScopy InChI
Affinity DataEC50:  2.31E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC62JKPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50299414(3-(benzo[d][1,3]dioxol-5-yl)-7-hydroxy-4H-chromen-...)copy SMILEScopy InChI
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC62JKPubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50299416(3'-methoxy-7-hydroxyisoflavone | CHEMBL573966)copy SMILEScopy InChI
Affinity DataEC50:  3.31E+4nMAssay Description:Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC62JKPubMed