Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50044771
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50434276(CHEMBL2386125)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029463(CHEMBL3343444)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50434275(CHEMBL2386128)copy SMILEScopy InChI
Affinity DataKi:  270nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029465(CHEMBL3343445)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029489(CHEMBL3343463)copy SMILEScopy InChI
Affinity DataKi:  560nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029491(CHEMBL3343464)copy SMILEScopy InChI
Affinity DataKi:  620nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029488(CHEMBL3343462)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50434277(CHEMBL2386127)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50434274(CHEMBL2386129)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029556(CHEMBL3343434)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50434278(CHEMBL2386126)copy SMILEScopy InChI
Affinity DataKi:  1.05E+4nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50029557(CHEMBL3343439)copy SMILEScopy InChI
Affinity DataKi:  1.47E+4nMAssay Description:Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumptionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3FJRPubMed