Found 4 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 7644 TargetSerine/threonine-protein kinase WNK2 [166-489](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.
Novartis Institutes for BioMedical Research, Inc.
Affinity DataIC50: 50nMpH: 7.3Assay Description:The assay utilized 5 to 10 nM of WNK1−4 protein compared to 25 nM used for mobility shift assay, enabling a more accurate comparison of selecti...More data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase WNK1 [1-491](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.
Novartis Institutes for BioMedical Research, Inc.
Affinity DataIC50: 64nMpH: 7.3Assay Description:The assay utilized 5 to 10 nM of WNK1−4 protein compared to 25 nM used for mobility shift assay, enabling a more accurate comparison of selecti...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK4 [1-444](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.
Novartis Institutes for BioMedical Research, Inc.
Affinity DataIC50: 187nMpH: 7.3Assay Description:The assay utilized 5 to 10 nM of WNK1−4 protein compared to 25 nM used for mobility shift assay, enabling a more accurate comparison of selecti...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase WNK3 [1-434](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.
Novartis Institutes for BioMedical Research, Inc.
Affinity DataIC50: 377nMpH: 7.3Assay Description:The assay utilized 5 to 10 nM of WNK1−4 protein compared to 25 nM used for mobility shift assay, enabling a more accurate comparison of selecti...More data for this Ligand-Target Pair
