Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50006407
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9V5TPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9V5TPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9V5TPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9V5TPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9V5TPubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University of Hradec Kralove

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged AKR1B10 expressed in Escherichia coli BL21 cells using all-trans-retinal as substrate incubate...More data for this Ligand-Target Pair