Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50010141
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50535489(CHEMBL4471729)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50138153(CHEMBL3754283)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50535491(CHEMBL4558962)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5DBTPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50535492(CHEMBL4558988)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5DBTPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50535490(CHEMBL4451091)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5DBTPubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50535493(CHEMBL4465524)copy SMILEScopy InChI
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human full length MAP4K4(1-1239)-G5-Avi-6His-Flag expressed in baculovirus-infected sf21 cells using His6-SMAD1 as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5DBTPubMed