Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50014328
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50574994(CHEMBL4847620)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM172038(US10155002, Compound 44 | US10647700, Compound EPZ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50574991(CHEMBL4854774)copy SMILES
Affinity DataIC50: 37nMAssay Description:Inhibition of EZH2 (unknown origin) using H3K27me0 peptide substrate incubated for 3 hrs by HMT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44V3JPubMed