Compile Data Set for Download or QSAR
Found 58 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50030218
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292638((+)-1'-(4-bromobenzyl)-N,3-diphenyl-3,4'-bipiperid...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292637((+)-1'-(4-bromobenzyl)-3-(2,4-difluorophenyl)-3,4'...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292667((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292648((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292670((+/-)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292673((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292672((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292669((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292666((+/-)-ethyl 1'-(4-bromobenzyl)-3-phenyl-3,4'-bipip...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292657((+/-)-3-(3-aminophenyl)-1'-(4-bromobenzyl)-3,4'-bi...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50211114((-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292640((-)-1'-(4-chloro-3-fluorobenzyl)-3-phenyl-3,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292642((+/-)-1'-(4-bromobenzyl)-3-(pyridin-2-yl)-3,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292674((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50018553((+)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292644((+/-)-1'-(4-bromobenzyl)-3-(pyridin-4-yl)-3,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292651((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292668((+/-)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperi...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50018553((+)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50018553((+)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292655((+/-)-1'-(4-bromobenzyl)-3-(3-(morpholine-4-carbon...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292671((+)-2-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50018560((+/-)-1'-(4-chlorobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292664((+/-)-1'-(4-bromobenzyl)-1-(methylthiomethyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292658((+/-)-1'-(4-bromobenzyl)-3-(3-hydroxyphenyl)-3,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292643((+/-)-1'-(4-bromobenzyl)-3-(pyridin-3-yl)-3,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292654((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292656((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292639((+/-)-1'-(3,4-dichlorobenzyl)-3-phenyl-3,4'-bipipe...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292645((+/-)-1'-(4-bromobenzyl)-3-(4-fluorophenyl)-3,4'-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292649((+/-)-1'-(4-bromobenzyl)-3-(3-chlorophenyl)-3,4'-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292647((+/-)-1'-(4-bromobenzyl)-3-(3-methoxyphenyl)-3,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292676((+/-)-1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292663((+/-)-1'-(4-bromobenzyl)-1-(2-methoxyethyl)-3-phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292665((+)-1-(1'-(4-bromobenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292677((+/-)-1'-(4-methylbenzyl)-3-phenyl-3,4'-bipiperidi...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292660((+/-)-1'-(4-bromobenzyl)-1-ethyl-3-phenyl-3,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292641((+/-)-1'-(4-chloro-3-(trifluoromethyl)benzyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292659((+/-)-1'-(4-bromobenzyl)-1-methyl-3-phenyl-3,4'-bi...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292652((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292653((+/-)-3-(1'-(4-bromobenzyl)-2,6-dioxo-3,4'-bipiper...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292679((+/-)-1'-(2,4-dichlorobenzyl)-3-phenyl-3,4'-bipipe...)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Johnson& Johnson PRD

Curated by ChEMBL
LigandPNGBDBM50292646((+/-)-1'-(4-bromobenzyl)-3-(4-methoxyphenyl)-3,4'-...)copy SMILEScopy InChI
Affinity DataIC50: 3.63E+3nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cells assessed as inhibition of ITAC-stimulated [35S]GTPgammaS binding pretreated 30 mins before ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0NQBPubMed
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