Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50039179
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320703(5-Benzoyl-8-methoxy-2,3,4,5-tetrahydro-1H-pyrido[4...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320710(5-(4-Chlorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320708(5-(3-Fluorobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320712(5-(4-Bromobenzoyl)-2-{3-[3-fluoro-5-(4-methoxytetr...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320706(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320716(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320704(5-Benzoyl-8-methanesulfonyl-2,3,4,5-tetrahydro-1Hp...)copy SMILEScopy InChI
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320711(2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France

Curated by ChEMBL
LigandPNGBDBM50320715(8-Fluoro-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B16PubMed