Compile Data Set for Download or QSAR
Found 10 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50048111
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50098551((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204671(CHEMBL3973160)copy SMILEScopy InChI
Affinity DataIC50: 5.57E+3nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204671(CHEMBL3973160)copy SMILEScopy InChI
Affinity DataIC50: 5.62E+3nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204674(CHEMBL3892079)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204674(CHEMBL3892079)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+3nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204673(CHEMBL3927929)copy SMILEScopy InChI
Affinity DataIC50: 1.98E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204673(CHEMBL3927929)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204666(CHEMBL3984812)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50204666(CHEMBL3984812)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+4nMAssay Description:Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2X36PubMed