Compile Data Set for Download or QSAR
Found 15 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50011059
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101832((E)-7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1...)copy SMILEScopy InChI
Affinity DataEC50:  43nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101827((Z)-7-{(1R,2R,3R)-2-[(E)-(S)-4-(1-Ethyl-cyclobutyl...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101823(4-(2-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-...)copy SMILEScopy InChI
Affinity DataEC50:  54nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101831((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101822((Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-o...)copy SMILEScopy InChI
Affinity DataEC50:  2.10nMAssay Description:Binding affinity towards human Prostanoid IP receptor in CHO cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101833((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)copy SMILEScopy InChI
Affinity DataEC50:  580nMAssay Description:Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101825((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101829(7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-pro...)copy SMILEScopy InChI
Affinity DataEC50:  32nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101819((Z)-7-{(1R,2R,3R)-2-[(E)-(S)-4-(1-Butyl-cyclobutyl...)copy SMILEScopy InChI
Affinity DataEC50:  71nMAssay Description:Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101834((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)copy SMILEScopy InChI
Affinity DataEC50:  220nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101853((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...)copy SMILEScopy InChI
Affinity DataEC50:  2.60nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101820((Z)-7-{(1R,2R,3R,5S)-5-Chloro-2-[(E)-(S)-4-(1-ethy...)copy SMILEScopy InChI
Affinity DataEC50:  39nMAssay Description:Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101818((Z)-7-{(1R,2S,3R)-2-[(E)-(S)-4-(1-Ethyl-cyclobutyl...)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101830((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...)copy SMILEScopy InChI
Affinity DataEC50:  2.80nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50101826((Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4...)copy SMILEScopy InChI
Affinity DataEC50:  45nMAssay Description:Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4H1TPubMed