Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50039774
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383861(CHEMBL2031160)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383786(CHEMBL2030807)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383865(CHEMBL2031169)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383862(CHEMBL2031168)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50217434(2S,4R,20S-4-{[2-carboxy-2-(2,4,6-trimethyl-benzoyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383863(CHEMBL2031162)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383779(CHEMBL2030815)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383864(CHEMBL2031163)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50383866(CHEMBL2031174)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9C3RPubMed