Compile Data Set for Download or QSAR
Found 29 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 8977
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433682(US10562878, Compound 263 | US10562878, Compound 28...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337818(CHEMBL1683876 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337838(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methylmetha...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433681(US10562878, Compound 256)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337851((1-(3,4-dichlorophenyl)cyclohexyl)methanamine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337821((1-(naphthalen-1-yl)cyclohexyl)methanamine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337820(CHEMBL1683898 | N-methyl-1-(1-(naphthalen-1-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent