Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50015181
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM258444(US9512130, 2)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM532292(JGS79C | N-(2,6-diethylphenyl)-2-[2-methoxy-4-(4-m...)copy SMILES
Affinity DataIC50: 4.70nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50583520(CHEMBL5094006)copy SMILES
Affinity DataIC50: 22nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157JCPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50583521(CHEMBL5077230)copy SMILES
Affinity DataIC50: 33nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase TTK(Homo sapiens (Human))TBA
LigandPNGBDBM50446445(CHEMBL2140523)copy SMILEScopy InChI
Affinity DataIC50: 429nMAssay Description:Displacement of tracer K9 from NanoLuc-fused MPS1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair