Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50032586
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331556(2-chloro-N-(4-(1-methyl-1H-pyrazol-3-ylamino)-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331557(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331558(CHEMBL1289536 | N-(1-amino-1,2-dioxopentan-3-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331575(2-chloro-N-(1-(1-methyl-1H-pyrazol-3-ylamino)-1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331574(2-chloro-N-(4-methyl-1-(1-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331555(CHEMBL1289305 | N-(1-(1H-pyrazol-3-ylamino)-1,2-di...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331572(CHEMBL1289423 | N-(4-(1H-pyrazol-3-ylamino)-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331573(CHEMBL1289535 | N-(4-amino-3,4-dioxobutan-2-yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331570(2-chloro-N-(4-(1-methyl-1H-pyrazol-3-ylamino)-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331569(2-chloro-N-(4-(5-methyl-1H-pyrazol-3-ylamino)-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 10.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331571(CHEMBL1289422 | N-(4-amino-3,4-dioxobutan-2-yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331568(CHEMBL1289193 | N-(4-(1H-pyrazol-3-ylamino)-3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331564(2-methyl-N-(1-oxobutan-2-yl)-3-(trifluoromethyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331553(2-chloro-N-(4-(methylamino)-3,4-dioxobutan-2-yl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 19.5nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331567(CHEMBL1289192 | N-(4-amino-3,4-dioxobutan-2-yl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 30.9nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331562(2-chloro-N-(1-oxobutan-2-yl)-3-(trifluoromethyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331563(2-fluoro-N-(1-oxobutan-2-yl)-3-(trifluoromethyl)be...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313461(4-propyl-6-(3-(trifluoromethyl)phenyl)pyrimidine-2...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331566(2-chloro-N-(1-oxopropan-2-yl)-3-(trifluoromethyl)b...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331565(2-methoxy-N-(1-oxobutan-2-yl)-3-(trifluoromethyl)b...)copy SMILEScopy InChI
Affinity DataIC50: 692nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331561(CHEMBL1288588 | N-(1-oxobutan-2-yl)-3-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331560(CHEMBL1288587 | N-(2-oxoethyl)-3-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331554(2-chloro-N-(4-(dimethylamino)-3,4-dioxobutan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331559(CHEMBL1288586 | N-(cyanomethyl)-3-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3KD0PubMed