Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50033378
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344131(6-(2,4-difluorophenoxy)-N-isopropyl-1H-pyrazolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344129(6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344123((R)-6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMedMMDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344134(CHEMBL1778102 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344135(CHEMBL1778101 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344137(CHEMBL1778099 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344123((R)-6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMedMMDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344130(6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 218nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMedMMDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344133(CHEMBL1778103 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 257nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344136(CHEMBL1778100 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344126(1-(4-(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344125(CHEMBL1778188 | [6-(2,4-Difluoro-phenoxy)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 795nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344138(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344128(CHEMBL1778185 | [6-(2,4-Difluoro-phenoxy)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344124((S)-6-(2,4-difluorophenoxy)-N-(1-(methylsulfonyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMedMMDB
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344132(CHEMBL1778104 | N-(6-(2,4-difluorophenoxy)-1H-pyra...)copy SMILEScopy InChI
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344127(6-(2,4-difluorophenoxy)-N-(2-(methylsulfonyl)ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26H4HR7PubMed