Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50001811
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50370182(CHEMBL4176038 | US11117865, Compound ZL0420)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069KMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50370181(CHEMBL4159382 | US11117865, Compound ZL0454)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069KMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50365262((+)-JQ1 | (S)-JQ1 (1) | CHEMBL1957266 | JQ1 | US10...)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069KMPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50103503(CHEMBL2393130 | US11117865, Compound RVX-208)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50370183(CHEMBL4173521)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of BRD4 in human SAE cells assessed as reduction in TLR3 agonist poly(I:C) -induced ISG56 RNA expression preincubated for 24 hrs followed ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X069KMPubMed