Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50010006
TargetPresenilin-1(Homo sapiens (Human))
FORUM Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM193081(US9193726, 69)copy SMILEScopy InChI
Affinity DataEC50:  8nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P74PubMed
TargetPresenilin-1(Homo sapiens (Human))
FORUM Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM193020(US9193726, 8)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P74PubMed
TargetPresenilin-1(Homo sapiens (Human))
FORUM Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM193021(US9193726, 9)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56P74PubMed