Compile Data Set for Download or QSAR
Found 11 Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50012101
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114703(CHEMBL287560 | N-[2-(5-Methoxy-2-phenyl-benzofuran...)copy SMILEScopy InChI
Affinity DataEC50:  0.0960nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114704(CHEMBL33549 | N-(2-(5-methoxy-2-(3-methoxybenzyl)b...)copy SMILEScopy InChI
Affinity DataEC50:  0.720nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114710(CHEMBL329299 | N-[2-(2-Cyclohexylmethyl-5-methoxy-...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114705(CHEMBL440144 | N-[2-(2-Benzyl-benzofuran-3-yl)-eth...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114723(CHEMBL96778 | N-{2-[5-Ethyl-2-(3-methoxy-benzyl)-b...)copy SMILEScopy InChI
Affinity DataEC50:  19nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114700(CHEMBL314947 | N-{2-[5-Methoxy-2-(3-trifluoromethy...)copy SMILEScopy InChI
Affinity DataEC50:  1.26nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114702(CHEMBL329960 | N-{2-[5-Methoxy-2-(2-methoxy-benzyl...)copy SMILEScopy InChI
Affinity DataEC50:  0.410nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114701(But-3-enoic acid {2-[5-methoxy-2-(3-methoxy-benzyl...)copy SMILEScopy InChI
Affinity DataEC50:  0.390nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)copy SMILEScopy InChI
Affinity DataEC50:  0.470nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMedDrugBank
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114707(But-3-enoic acid [2-(2-benzyl-5-methoxy-benzofuran...)copy SMILEScopy InChI
Affinity DataEC50:  0.170nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Institut de Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50114715(CHEMBL317742 | N-{2-[5-Methoxy-2-(4-methoxy-benzyl...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Intrinsic activity at human Melatonin receptor type 1B evaluated on [35S]-GTP-gammaS, binding in Chinese hamster ovarian (CHO) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52P0WPubMed