Compile Data Set for Download or QSAR
Found 21 Enz. Inhib. hit(s) with all data for assayid = 8 entry = 50036796
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074896(2-[4-(6-Ethoxy-2,3-bis-hydroxymethyl-7-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026877(CHEMBL12346)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074886(2-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074894(2-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074884(2-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074901(2-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074889(1-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074887(1-[4-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074897(2-[4-(7-Ethoxy-2,3-bis-hydroxymethyl-6-methoxy-nap...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026876(CHEMBL543965)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026880(CHEMBL543017)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074893(2-[4-(6,7-Diethoxy-2,3-bis-hydroxymethyl-naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074890(4'-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026874(CHEMBL556787)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026875(CHEMBL537252)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026878(CHEMBL556982)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50026873(CHEMBL542296)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074895(2-[4-(2,3-Bis-hydroxymethyl-naphthalen-1-yl)-pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50074903(2-[5-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed