Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with all data for assayid = 9 entry = 50046923
TargetBeta-secretase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138463(CHEMBL3753957)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human BACE-1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition measured after 15 mins by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J5XPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138429(CHEMBL3752926)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of recombinant human BACE-1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition measured after 15 mins by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J5XPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138282(CHEMBL3753360)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of recombinant human BACE-1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition measured after 15 mins by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J5XPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50138279(CHEMBL3752467)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of recombinant human BACE-1 using M-2420 as substrate preincubated for 1 hr followed by substrate addition measured after 15 mins by FRET ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J5XPubMed